Critical evaluation of observed adverse effects of endocrine active substances on reproduction and development, the immune system, and the nervous system

@article{OConnor2003CriticalEO,
  title={Critical evaluation of observed adverse effects of endocrine active substances on reproduction and development, the immune system, and the nervous system},
  author={J. C. O'Connor and R. E. Chapin},
  journal={Pure and Applied Chemistry},
  year={2003},
  volume={75},
  pages={2099 - 2123}
}
  • J. C. O'Connor, R. E. Chapin
  • Published 2003
  • Chemistry
  • Pure and Applied Chemistry
  • The last 40 years have seen many reports that man-made chemicals and environmental pollutants cause adverse effects in humans and wildlife; however, actually linking an exposure with a mechanism and an effect has yet to be done for endocrine disruption. Certainly, studies in experimental animals have shown that sufficient doses of select compounds can disrupt the endocrine system and produce the attendant adverse outcomes. The purpose of this contribution is to evaluate some of the recent… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 157 REFERENCES
    Pure and Applied Chemistry
    • 362
    • PDF
    Neurotoxicology
    • 270
    • PDF
    Teratology
    • 111
    • PDF
    Adverse effects of endocrine active substances
    • 1995
    Adverse effects of endocrine active substances
    • 2000
    Am. J. Reprod. Immunol
    • 1994
    Ann. Med. (Helsinki)
    • 1999
    Annu. Rev. Pharmacol. Toxicol
    • 1982