Critical evaluation of in silico methods for prediction of coiled-coil domains in proteins

@article{Li2016CriticalEO,
  title={Critical evaluation of in silico methods for prediction of coiled-coil domains in proteins},
  author={Chen Li and Catherine Ching Han Chang and Jeremy Nagel and Benjamin T. Porebski and Morihiro Hayashida and Tatsuya Akutsu and Jiangning Song and Ashley M. Buckle},
  journal={Briefings in bioinformatics},
  year={2016},
  volume={17 2},
  pages={
          270-82
        }
}
Coiled-coils refer to a bundle of helices coiled together like strands of a rope. It has been estimated that nearly 3% of protein-encoding regions of genes harbour coiled-coil domains (CCDs). Experimental studies have confirmed that CCDs play a fundamental role in subcellular infrastructure and controlling trafficking of eukaryotic cells. Given the… CONTINUE READING