Critical Roles of the Na+/K+-ATPase in Apoptosis and CNS Diseases

@inproceedings{Sproul2009CriticalRO,
  title={Critical Roles of the Na+/K+-ATPase in Apoptosis and CNS Diseases},
  author={Alistair B. Sproul and Xin Zhou and Shan Ping Yu},
  year={2009}
}
The Na+/K+-ATPase is a transmembrane protein that serves as the primary electrogenic ion transporter in the plasma membrane of all mammalian cells. In addition to this critical ubiquitous function, the Na+/K+-ATPase is also essential for several important tissue-specific functions, which include Na+ resorption in the kidney, muscular contraction in cardiac and skeletal myocytes, and membrane repo-larization. Although the Na+/K+-ATPase was first discovered in neuronal tissue, its function has… CONTINUE READING

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