Criteria for identifying the molecular basis of the engram (CaMKII, PKMzeta)

@inproceedings{Lisman2017CriteriaFI,
  title={Criteria for identifying the molecular basis of the engram (CaMKII, PKMzeta)},
  author={John E. Lisman},
  booktitle={Molecular Brain},
  year={2017}
}
The engram refers to the molecular changes by which a memory is stored in the brain. Substantial evidence suggests that memory involves learning-dependent changes at synapses, a process termed long-term potentiation (LTP). Thus, understanding the storages process that underlies LTP may provide insight into how the engram is stored. LTP involves induction, maintenance (storage), and expression sub-processes; special tests are required to specifically reveal properties of the storage process. The… CONTINUE READING
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