Crimean-Congo hemorrhagic fever virus delays activation of the innate immune response.

Abstract

As a first line of defence against virus infection, mammalian cells elicit an innate immune response, characterized by secretion of type I interferons and the up-regulation of interferon stimulated genes. Many viruses down-regulate the innate immune responses in order to enhance their virulence. Crimean-Congo hemorrhagic fever virus (CCHFV), a Nairovirus of… (More)
DOI: 10.1002/jmv.21222

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