Creutzfeldt-Jakob disease.

  title={Creutzfeldt-Jakob disease.},
  author={Yasushi Iwasaki},
  journal={Neuropathology : official journal of the Japanese Society of Neuropathology},
  volume={37 2},
This review will explore the clinical and pathological findings of the various forms of Creutzfeldt-Jakob disease (CJD). Clinical findings of CJD are characterized by rapidly progressive cognitive dysfunction, diffusion-weighted magnetic resonance imaging (DWI) hyperintensity, myoclonus, periodic sharp-wave complexes on electroencephalogram and akinetic mutism state. Neuropathologic findings of CJD are characterized by spongiform changes in gray matter, gliosis-particularly hypertrophic… CONTINUE READING
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