Crescentic nodular glomerulosclerosis secondary to truncated immunoglobulin alpha heavy chain deposition.

@article{Cheng1996CrescenticNG,
  title={Crescentic nodular glomerulosclerosis secondary to truncated immunoglobulin alpha heavy chain deposition.},
  author={Ignatius K p Cheng and Stephen Ka Nung Ho and Daniel T. Chan and Wing K. Ng and Kwok Wah Chan},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={1996},
  volume={28 2},
  pages={283-8}
}
Nodular glomerulosclerosis secondary to deposition of monoclonal immunoglobulin (Ig) light chains with or without heavy chains is a recognized clinicopathological entity. Recent reports have demonstrated that an identical glomerular lesion may also occur as a result of truncated tau Ig heavy chain deposition. We investigated the nature of Ig deposits in a patient who presented with rapidly progressive renal failure secondary to crescentic nodular glomerulosclerosis. This patient had a relapsing… CONTINUE READING

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