Creation of macropores in three-dimensional bacterial cellulose scaffold for potential cancer cell culture.

@article{Xiong2014CreationOM,
  title={Creation of macropores in three-dimensional bacterial cellulose scaffold for potential cancer cell culture.},
  author={Guangyao Xiong and Honglin Luo and Yong Zhu and Sudha R. Raman and Yizao Wan},
  journal={Carbohydrate polymers},
  year={2014},
  volume={114},
  pages={553-7}
}
There is an increasing need for an effective in vitro model that can resemble the 3-D nature of tumor microenvironments. In this work, a 3-D bacterial cellulose (BC) scaffold with macropores was fabricated by a facile freeze drying method for potential culture of cancer cells. This in vitro study reported, for the first time, the role of macropores in the adjustment of cancer cell behavior when compared with previous results cultured in BC scaffolds without macropores. The scaffold was… CONTINUE READING

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