Creating tissue microarrays by cutting-edge matrix assembly.

  title={Creating tissue microarrays by cutting-edge matrix assembly.},
  author={Hallgeir Rui and Matthew J. LeBaron},
  journal={Expert review of medical devices},
  volume={2 6},
Tissue microarrays have become widely adopted for effective parallel in situ analysis of hundreds of tissues placed onto single slides. Traditionally, tissue core punches are transferred into predrilled holes within a scaffold block of paraffin or other material, and sectioned transversely by a microtome to generate array sections. While core-based arraying has greatly advanced tissue analyses, some of the limitations include restricted feature sizes and numbers, variable core depths of… CONTINUE READING
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