Creating and evaluating genetic tests predictive of drug response

  title={Creating and evaluating genetic tests predictive of drug response},
  author={Scott T. Weiss and Ping Liao and David A. Flockhart and M. Eileen Dolan and Neal L. Benowitz and Julie A. Johnson and Mark J. Ratain and Kathleen M. Giacomini},
  journal={Nature Reviews Drug Discovery},
A key goal of pharmacogenetics — the use of genetic variation to elucidate inter-individual variation in drug treatment response — is to aid the development of predictive genetic tests that could maximize drug efficacy and minimize drug toxicity. The completion of the Human Genome Project and the associated HapMap Project, together with advances in… CONTINUE READING