Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats.

@article{Shear2000CreatineR3,
  title={Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats.},
  author={Deborah A. Shear and K L Haik and Gary L Dunbar},
  journal={Neuroreport},
  year={2000},
  volume={11 9},
  pages={
          1833-7
        }
}
This study assessed whether creatine could attenuate 3-nitropropionic acid (3NP)-induced neuropathological and behavioral abnormalities that are analogous to those observed in Huntington's disease (HD). Rats were fed diets containing either 1% creatine or normal rat chow for 2 weeks prior to the onset of 3NP administration, and for the duration of the study. 3NP was administered systemically in gradually increasing concentrations over an 8-week testing period. Results show that creatine can… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

Similar Papers

Loading similar papers…