Creatine as a food supplement for the general population

@article{Ostoji2021CreatineAA,
  title={Creatine as a food supplement for the general population},
  author={Sergej M. Ostoji{\'c}},
  journal={Journal of Functional Foods},
  year={2021},
  volume={83},
  pages={104568}
}
  • S. Ostojić
  • Published 1 August 2021
  • Medicine
  • Journal of Functional Foods

Low Tissue Creatine: A Therapeutic Target in Clinical Nutrition

This mini review paper summarizes disorders with deficient creatine levels and provides arguments for assessing and employing tissue creatine as a relevant target in clinical nutrition.

Could dietary creatine intake modulate overweight elderly's selective attention and inhibitory function?

The results suggest that in elderly women with overweight that dietary intake of creatine may influence cognitive ability, and support the idea that intake of dietary creatine may be an important factor for cognition in older adults.

References

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Creatine: endogenous metabolite, dietary, and therapeutic supplement.

It is evident that creatine plays a critical, though underappreciated, role in brain function.

Clinical pharmacology of the dietary supplement creatine monohydrate.

This review covers the basics of creatine synthesis and transport, proposed mechanisms of action, pharmacokinetics of exogenous creatine administration, creatine use in disease models, side effects associated with use, and issues on product quality.

Creatine is a Conditionally Essential Nutrient in Chronic Kidney Disease: A Hypothesis and Narrative Literature Review

It is hypothesized that with increasing degree of CKD, creatine coming from meat and dairy in food increasingly becomes an essential nutrient, which may be a creatine deficiency with important contributions to the sarcopenia, fatigue, impaired quality of life, impaired cognition, and premature mortality seen in CKD.

The influence of creatine supplementation on the cognitive functioning of vegetarians and omnivores

In vegetarians rather than in those who consume meat, creatine supplementation resulted in better memory, and irrespective of dietary style, the supplementation of creatine decreased the variability in the responses to a choice reaction-time task.

Creatine in Health and Disease

It can be concluded that creatine supplementation has several health and therapeutic benefits throughout the lifespan.

Cognitive effects of creatine ethyl ester supplementation

Although creatine seems to facilitate cognition on some tasks, these results require replication using objective measures of compliance, and the improvement is discussed in the context of research examining the influence of brain energy capacity on cognitive performance.

Creatine--its chemical synthesis, chemistry, and legal status.

This chapter will serve as a survey of the paths of chemical synthesis of creatine, its chemistry, properties, stability, analytical determination methods and legal status.

Creatine supplementation improves performance, but is it safe? Double-blind placebo-controlled study.

Despite the expected weight increase, the creatine monohydrate supplementation is safe for health and no detrimental effects on different organs and physiological systems were observed in the cohort of volunteers.

Effects of Creatine Supplementation on Properties of Muscle, Bone, and Brain Function in Older Adults: A Narrative Review

A narrative review of the small body of research investigating the effects of creatine supplementation alone on measures of muscle mass and performance, bone mineral and strength, and indices of brain health in older adults finds Creatine has the potential to have favorable effects on muscle, bone, and brain health (independent of exercise) in Older adults.

Dietary creatine intake and depression risk among U.S. adults

A significant negative relationship between dietary creatine and depression in a nationally representative adult cohort is indicated and further research is warranted to investigate the role creatine plays in depression, particularly among women and across the lifespan.
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