Creatine and guanidinoacetate content of human milk and infant formulas: implications for creatine deficiency syndromes and amino acid metabolism

@article{Edison2013CreatineAG,
  title={Creatine and guanidinoacetate content of human milk and infant formulas: implications for creatine deficiency syndromes and amino acid metabolism},
  author={Erica E Edison and Margaret E Brosnan and Khalid Aziz and John T Brosnan},
  journal={British Journal of Nutrition},
  year={2013},
  volume={110},
  pages={1075 - 1078}
}
Creatine is essential for normal neural development; children with inborn errors of creatine synthesis or transport exhibit neurological symptoms such as mental retardation, speech delay and epilepsy. Creatine accretion may occur through dietary intake or de novo creatine synthesis. The objective of the present study was to determine how much creatine an infant must synthesise de novo. We have calculated how much creatine an infant needs to account for urinary creatinine excretion (creatine's… 
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Methionine metabolism in Yucatan miniature swine.
  • Laura E McBreairty
  • Medicine
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
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TLDR
The results of this thesis demonstrate that the presence of IUGR, an increased demand for creatine synthesis, or the supplementation with remethylation nutrients can each affect methionine availability; all are important when considering neonatal nutrient requirements.
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