Creatine Supplementation and Exercise Performance

@article{Bemben2005CreatineSA,
  title={Creatine Supplementation and Exercise Performance},
  author={Michael G. Bemben and Hugh S. Lamont},
  journal={Sports Medicine},
  year={2005},
  volume={35},
  pages={107-125}
}
AbstractCreatine monohydrate (Cr) is perhaps one of the most widely used supplements taken in an attempt to improve athletic performance. The aim of this review is to update, summarise and evaluate the findings associated with Cr ingestion and sport and exercise performance with the most recent research available. Because of the large volume of scientific literature dealing with Cr supplementation and the recent efforts to delineate sport-specific effects, this paper focuses on research… Expand
Creatine Supplementation and Women Athletes
TLDR
The purpose of this chapter was to examine the morphological potential for women to respond to Cr supplementation, and its effects on exercise performance and body composition. Expand
Risk assessment for creatine monohydrate.
TLDR
The OSL risk assessment method indicates that the evidence of safety is strong at intakes up to 5 g/d for chronic supplementation, and this level is identified as the OSL. Expand
MUSCLE METABOLISM AND FATIGUE DURING SPRINT EXERCISE: EFFECTS OF CREATINE SUPPLEMENTATION
TLDR
Research is needed to investigate and substantiate the effects of combining Cr supplementation with long term training on single and repeated sprints performance, and to show why even a small improvement may be important for competitive athletes. Expand
Creatine Supplementation in Endurance Sports
Creatine (Cr) is a compound that is synthesized endogenously in the kidneys, liver, and pancreas by the transamidination and subsequent transmethylation of three constituent amino acids: glycine,Expand
Beyond muscles: The untapped potential of creatine.
TLDR
There is evidence to suggest that individuals with certain neurological conditions may benefit from exogenous creatine supplementation if treatment protocols can be optimized and there is increasing evidence that creatine may have a regulatory impact on the immune system. Expand
Effect of different doses of creatine supplementation on endogenous creatine synthesis
TLDR
The present study investigated the effect of supplementation with 0, 0.75, 1.0 and 6.0 g Cre/kg body weight per d for 4 weeks on L-AGAT activity and GAA concentration in the kidneys and total Cre in the gastrocnemius muscle in adult male Sprague-Dawley rats. Expand
Creatine Supplementation Associated with Resistance Training Does Not Alter Renal and Hepatic Functions 03 ARTIGO RBME 526
TLDR
It is concluded that creatine supplementation at the dosages used for healthy subjects during eight weeks does not alter hepatic or renal function, hence under the conditions of this study, creatine was considered safe. Expand
Effects of creatine monohydrate supplementation on simulated soccer performance.
TLDR
Acute short-term Cr supplementation has no beneficial effect on physical measures obtained during a 90-min soccer-simulation test, thus bringing into question its potential as an effective ergogenic aid for soccer players. Expand
Muscle strength and muscle endurance: with and without creatine supplementation.
TLDR
The results indicated that Muscle endurance was improved better in the EG and supplementation of creatine monohydrate supplements is useful to improve both muscular strength and muscular endurance. Expand
The effects of Creatine Long-Term Supplementation on Muscle Morphology and Swimming Performance in Rats.
TLDR
Long-term creatine supplementation increase muscle hypertrophy (but not body weight) and enhance endurance swimming performance in rats is suggested to have increased the number of muscle fibers and enhanced endurance swimmingperformance in rats. Expand
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References

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TLDR
Creatinine is synthesised from the amino acids glycine, arginine and methionine in the kidneys, liver and pancreas, and is predominantly found in skeletal muscle, where it exists in 2 forms. Expand
American College of Sports Medicine roundtable. The physiological and health effects of oral creatine supplementation.
TLDR
Although Cr supplementation exhibits small but significant physiological and performance changes, the increases in performance are realized during very specific exercise conditions, suggesting that the apparent high expectations for performance enhancement, evident by the extensive use of Cr supplementation, are inordinate. Expand
Oral Creatine Supplementation and Skeletal Muscle Metabolism in Physical Exercise
TLDR
There is a shortage of scientific evidence concerning the adverse effects following creatine supplementation in healthy individuals even with long-term dosage, so creatine may be considered as a widespread, effective and safe ergogenic aid. Expand
A Review of Creatine Supplementation: Side Effects and Improvements in Athletic Performance
TLDR
It is recommended that children, adolescents, pregnant women, and people with diabetes or renal disease avoid creatine supplementation due to its unknown effects on these special populations. Expand
Scientific facts behind creatine monohydrate as sport nutrition supplement.
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  • Medicine
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TLDR
In this article, scientific facts and considerations are presented, which support the concept of possible risks of uncontrolled supplementation in athletes with pure Cr.H2O overdosing, and a practical approach for detecting altered links in Cr metabolism and biosynthesis under conditions ofpure Cr. Expand
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TLDR
In this chapter the actions of creatine (Cr) and creatine phosphate (PCr), on muscle metabolism and performance are discussed and it is reported that three out of eight subjects studied showed no beneficial effects. Expand
Adverse Effects of Creatine Supplementation
TLDR
There is no evidence for deleterious effects in healthy individuals of creatine supplementation, but idiosyncratic effects may occur when large amounts of an exogenous substance containing an amino group are consumed, with the consequent increased load on the liver and kidneys. Expand
Effect of oral creatine supplementation on jumping and running performance.
TLDR
The results show that Cr supplementation helps to prolong the time during which the maximal rate of power output could be maintained and the time of intensive running up to exhaustion improved by 13%. Expand
The Effect of Creatine Supplementation on Anaerobic Performance in Moderately Active Men
The effect of creatine monohydrate (Cr) supplementation on anaerobic performance was investigated in 21 (treatment = 11; placebo = 10) moderately active males. Supplementation included 20 g·d−1 of CrExpand
Effects of 30 days of creatine ingestion in older men
TLDR
The data suggest that 30 days of Cr-supplementation may have a beneficial effect on reducing muscle fatigue in men over the age of 60 years, but it does not affect body composition or strength. Expand
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