Creatine Kinase Level and Lipid Peroxidation Rate in Human Spermatozoa from Patients with Cancer

@article{Sidhu1997CreatineKL,
  title={Creatine Kinase Level and Lipid Peroxidation Rate in Human Spermatozoa from Patients with Cancer},
  author={Rajinder S. Sidhu and Yongjin Wang and Ashok Agarwal},
  journal={Journal of Assisted Reproduction and Genetics},
  year={1997},
  volume={14},
  pages={538-542}
}
Purpose: The present study assessed whether the poor semen quality in patients with cancer results from the inhibition of sperm maturation as indicated by creatine kinase or from increased oxidative stress as assessed by lipid peroxidation of the sperm membrane. Methods: Cryopreserved semen specimens from patients with testicular (n = 10) and nontesticular (n = 12) cancer and normal healthy donors (n = 14) were analyzed for lipid peroxidation and creatine kinase levels. Results: The levels of… CONTINUE READING