Crawling and Gliding: A Computational Model for Shape-Driven Cell Migration

Abstract

Cell migration is a complex process involving many intracellular and extracellular factors, with different cell types adopting sometimes strikingly different morphologies. Modeling realistically behaving cells in tissues is computationally challenging because it implies dealing with multiple levels of complexity. We extend the Cellular Potts Model with an… (More)
DOI: 10.1371/journal.pcbi.1004280

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