Craniofacial muscle engineering using a 3-dimensional phosphate glass fibre construct.

@article{Shah2005CraniofacialME,
  title={Craniofacial muscle engineering using a 3-dimensional phosphate glass fibre construct.},
  author={Rishma Shah and Andrea C M Sinanan and Jonathan C Knowles and Nigel P Hunt and Mark P Lewis},
  journal={Biomaterials},
  year={2005},
  volume={26 13},
  pages={1497-505}
}
The current technique to replace missing craniofacial skeletal muscle is the surgical transfer of local or free flaps. This is associated with donor site morbidity, possible tissue rejection and limited supply. The alternative is to engineer autologous skeletal muscle in vitro, which can then be re-implanted into the patient. A variety of biomaterials have been used to engineer skeletal muscle with limited success. This study investigated the use of phosphate-based glass fibres as a potential… CONTINUE READING