Craniofacial divergence by distinct prenatal growth patterns in Fgfr2 mutant mice

@inproceedings{Perrine2013CraniofacialDB,
  title={Craniofacial divergence by distinct prenatal growth patterns in Fgfr2 mutant mice},
  author={Susan M Motch Perrine and Theodore M. Cole and Neus Mart{\'i}nez-Abad{\'i}as and Kristina J Aldridge and Ethylin Wang Jabs and Joan T. Richtsmeier},
  booktitle={BMC Developmental Biology},
  year={2013}
}
Differences in cranial morphology arise due to changes in fundamental cell processes like migration, proliferation, differentiation and cell death driven by genetic programs. Signaling between fibroblast growth factors (FGFs) and their receptors (FGFRs) affect these processes during head development and mutations in FGFRs result in congenital diseases including FGFR-related craniosynostosis syndromes. Current research in model organisms focuses primarily on how these mutations change cell… CONTINUE READING
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