Craniofacial defects in mice lacking BMP type I receptor Alk2 in neural crest cells

@article{Duds2004CraniofacialDI,
  title={Craniofacial defects in mice lacking BMP type I receptor Alk2 in neural crest cells},
  author={Marek Dud{\'a}s and Somyoth Sridurongrit and Andr{\'e} Louis Lobo Nagy and Kenji Okazaki and Vesa M Kaartinen},
  journal={Mechanisms of Development},
  year={2004},
  volume={121}
}
Neural crest cells (NCCs) are pluripotent migratory cells that contribute to the development of various craniofacial structures. Many signaling molecules have been implicated in the formation, migration and differentiation of NCCs including bone morphogenetic proteins (BMPs). BMPs signal through a receptor complex composed of type I and type II receptors. Type I receptors (Alk2, Alk3 and Alk6) are the primary determinants of signaling specificity and therefore understanding their function is… CONTINUE READING

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View 6 Excerpts
Highly Influenced

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View 1 Excerpt

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References

Publications referenced by this paper.
Showing 1-10 of 34 references

Region- and stage-specific effects of FGFs and BMPs in chick mandibular morphogenesis.

Developmental dynamics : an official publication of the American Association of Anatomists • 2002
View 1 Excerpt

Regulation of cell proliferation by Smad proteins

P. ten Dijke, Goumans, M.-J, F. Itoh, S. Itoh
J. Cell. Physiol • 2002

Smad signalling network.

Journal of cell science • 2002

Craniofacial development and patterning.

Methods in molecular biology • 2000
View 2 Excerpts

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