Cranial ontogeny in the direct-developing frog, Eleutherodactylus coqui (Anura: Leptodactylidae), analyzed using whole-mount immunohistochemistry.

@article{Hanken1992CranialOI,
  title={Cranial ontogeny in the direct-developing frog, Eleutherodactylus coqui (Anura: Leptodactylidae), analyzed using whole-mount immunohistochemistry.},
  author={James Hanken and Michael W Klymkowsky and Cliff H. Summers and Daniel W. Seufert and N Ingebrigtsen},
  journal={Journal of morphology},
  year={1992},
  volume={211 1},
  pages={95-118}
}
Direct development in amphibians is an evolutionarily derived life-history mode that involves the loss of the free-living, aquatic larval stage. We examined embryos of the direct-developing anuran Eleutherodactylus coqui (Leptodactylidae) to evaluate how the biphasic pattern of cranial ontogeny of metamorphosing species has been modified in the evolution of direct development in this lineage. We employed whole-mount immunohistochemistry using a monoclonal antibody against the extracellular… CONTINUE READING

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