Cranial neurotransmitter alteration in newborn piglets exposed to oxygen.

BACKGROUND To evaluate the influence of hyperoxia on neurotransmitters in the developing brain of newborn piglets. METHODS Ten newborn piglets were randomly assigned to hyperoxia (inhaled 100% oxygen) or control (inhaled room air) groups and ventilated for 4 hours. Blood samples were obtained at 0, 15, 30, and then every 30 minutes for 4 hours. Extracts… CONTINUE READING