Cranberry juice ingestion and clinical drug-drug interaction potentials; review of case studies and perspectives.

@article{Srinivas2013CranberryJI,
  title={Cranberry juice ingestion and clinical drug-drug interaction potentials; review of case studies and perspectives.},
  author={Nuggehally R. Srinivas},
  journal={Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques},
  year={2013},
  volume={16 2},
  pages={
          289-303
        }
}
Cranberry juice is a popular beverage with many health benefits. It has anthocyanins to supplement dietary needs. Based on in vitro evidence cranberry juice is an inhibitor of CYP enzymes and at higher amounts as potent as ketoconazole (CYP3A) and fluconazole (CYP2C9). There is, however, a discrepancy between in vitro and in vivo observations with respect to a number of substrates (cyclosporine, warfarin, flurbiprofen, tizanidine, diclofenac, amoxicillin, ceflacor); with the exception of a… CONTINUE READING

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