Cranberry and Urinary Tract Infections

@article{Guay2012CranberryAU,
  title={Cranberry and Urinary Tract Infections},
  author={David R. P. Guay},
  journal={Drugs},
  year={2012},
  volume={69},
  pages={775-807}
}
Urinary tract infection (UTI) refers to the presence of clinical signs and symptoms arising from the genitourinary tract plus the presence of one or more micro-organisms in the urine exceeding a threshold value for significance (ranges from 102 to 103 colony-forming units/mL). Infections are localized to the bladder (cystitis), renal parenchyma (pyelonephritis) or prostate (acute or chronic bacterial prostatitis). Single UTI episodes are very common, especially in adult women where there is a… Expand
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References

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Cranberry and Prevention of Urinary Tract Infections in Children
TLDR
A meta-analysis arrived at the conclusion that antibiotic prophylaxis is associated with a meaningful reduction in the risk of UTI infection, and the peculiar characteristics of this natural element and its possible use in the prevention ofUTI are introduced. Expand
Contemporary Management of Uncomplicated Urinary Tract Infections
TLDR
The ever-increasing incidence of antimicrobial resistance of the common uropathogens in uUTI has been and is a continuing focus of intensive study, resulting in substantial cost savings. Expand
Can a concentrated cranberry extract prevent recurrent urinary tract infections in women? A pilot study.
TLDR
A cranberry preparation with a high phenolic content may completely prevent UTIs in women who are subject to recurrent infections. Expand
Efficacy of cranberry in prevention of urinary tract infection in a susceptible pediatric population.
TLDR
Liquid cranberry products, on a daily basis, at the dosage employed, did not have any effect greater than that of water in preventing urinary tract infections in this pediatric neuropathic bladder population. Expand
Cranberry or trimethoprim for the prevention of recurrent urinary tract infections? A randomized controlled trial in older women
TLDR
The findings will allow older women with recurrent UTIs to weigh up with their clinicians the inherent attractions of a cheap, natural product like cranberry extract whose use does not carry the risk of antimicrobial resistance or super- infection with Clostridium difficile or fungi. Expand
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TLDR
Cranberry is commonly used therapeutically among patients seen in a pediatric nephrology clinic and is perceived as useful by parents, though uncommonly discussed with physicians, and Randomized controlled trials are needed to determine the effectiveness of cranberry juice therapy for rUTI in children. Expand
Do cranberries help prevent urinary tract infections?
TLDR
Cranberries are widely used in the treatment and prevention of urinary tract infections (UTIs) and for those at risk of such infections and are thought to be the key factors in inhibiting E. coli adherence. Expand
Predictability of Methenamine Efficacy Based on Type of Urinary Pathogen and pH
TLDR
In Foley catheter patients with chronic asymptomatic chronic bacteriuria secondary to Proteus, Pseudomonas or E. coli infection, the type of urinary pathogen or the urinary pH cannot be used to predict the efficacy of methenamine therapy either with or without urinary acidifying agents. Expand
Effect of cranberry juice on bacteriuria in children with neurogenic bladder receiving intermittent catheterization.
TLDR
The frequency of bacteriuria in patients with neurogenic bladder receiving intermittent catheterization is 70%; cranberry concentrate had no effect on bacteriuri in this population. Expand
Cranberry juice for prophylaxis of urinary tract infections--conclusions from clinical experience and research.
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  • Medicine
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
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TLDR
Experimental research has identified an anti-adhesive mechanism of cranberry juice that prevents docking of bacteria on host tissues and appears to be due to proanthocyanidins with an A-type linkage of flavanols. Expand
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