CpG oligodeoxynucleotides improve the response to hepatitis B immunization in healthy and SIV-infected rhesus macaques

@article{Verthelyi2004CpGOI,
  title={CpG oligodeoxynucleotides improve the response to hepatitis B immunization in healthy and SIV-infected rhesus macaques},
  author={D. Verthelyi and V. Wang and J. Lifson and D. Klinman},
  journal={AIDS},
  year={2004},
  volume={18},
  pages={1003-1008}
}
Objective: The development of an immunogenic vaccine against hepatitis B virus (HBV) is particularly important for HIV-infected patients since shared epidemiological risks result in HIV-infected subjects having a high incidence of HBV, and coinfection with HBV increases the occurrence of hepatotoxicity with antiretroviral therapy. Although HBV vaccination is recommended to all HIV-positive patients, its efficacy in these patients is reduced. Methods: Healthy (n = 15) and SIV-infected (n = 17… Expand
Predictors of humoral response to recommended vaccines in HIV-infected adults.
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