CpG methylation of promoter region inactivates E-cadherin gene in renal cell carcinoma.

Abstract

CpG methylation in the promoter region has been shown to be important in the regulation of genes implicated in malignant transformation. The present study was designed to test the hypothesis that CpG methylation of the promoter region of the E-cadherin gene may inactivate its expression in renal cell carcinoma. To test this hypothesis, five kidney cancer… (More)

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@article{Nojima2001CpGMO, title={CpG methylation of promoter region inactivates E-cadherin gene in renal cell carcinoma.}, author={Dana Nojima and Kenichi Nakajima and L C Li and Joseph H Franks and Leopoldo Alves Ribeiro-Filho and Norito Ishii and Rajvir Dahiya}, journal={Molecular carcinogenesis}, year={2001}, volume={32 1}, pages={19-27} }