CpG islands in human ZFX and ZFY and mouse Zfx genes: sequence similarities and methylation differences.
@article{Luoh1995CpGII,
title={CpG islands in human ZFX and ZFY and mouse Zfx genes: sequence similarities and methylation differences.},
author={Shiuh-Wen Luoh and Karin Jegalian and A Lee and Ellson Y. Chen and Anne Ridley and David C. Page},
journal={Genomics},
year={1995},
volume={29 2},
pages={
353-63
}
}The human ZFX, human ZFY, and mouse Zfx genes have CpG islands near their 5; ends. These islands are typical in that they span about 1.5 kb, contain transcription initiation sites, and encompass some 5' untranslated exons and introns. However, comparitive nucleotide sequencing of these human and mouse islands provided evidence of evolutionary conservation to a degree unprecedented among mammalian 5' CpG islands. In one stretch of 165 nucleotides containing 19 CpGs, mouse Zfx and human ZFX are…
28 Citations
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