CpG island hypermethylation frequently silences FILIP1L isoform 2 expression in prostate cancer.

Abstract

PURPOSE Senescence related regulatory pathways serve as barriers to cancer immortalization and progression but they are currently not well defined. FILIP1L is a growth inhibitory gene with multiple isoforms whose expression is increased in senescent prostate and prostate cancer cells, and decreased in many cancers. We investigated whether DNA methylation… (More)
DOI: 10.1016/j.juro.2012.08.188

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@article{Desotelle2013CpGIH, title={CpG island hypermethylation frequently silences FILIP1L isoform 2 expression in prostate cancer.}, author={Joshua A Desotelle and Matthew Truong and Jonathan A. Ewald and Pushpa Weeratunga and Bing Yang and Wei Huang and David Frasier Jarrard}, journal={The Journal of urology}, year={2013}, volume={189 1}, pages={329-35} }