CpG dinucleotides and the mutation rate of non-CpG DNA.

@article{Walser2008CpGDA,
  title={CpG dinucleotides and the mutation rate of non-CpG DNA.},
  author={Jean-Claude Walser and Lo{\"i}c Ponger and Anthony V. Furano},
  journal={Genome research},
  year={2008},
  volume={18 9},
  pages={
          1403-14
        }
}
The neutral mutation rate is equal to the base substitution rate when the latter is not affected by natural selection. Differences between these rates may reveal that factors such as natural selection, linkage, or a mutator locus are affecting a given sequence. We examined the neutral base substitution rate by measuring the sequence divergence of approximately 30,000 pairs of inactive orthologous L1 retrotransposon sequences interspersed throughout the human and chimpanzee genomes. In contrast… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 36 CITATIONS, ESTIMATED 34% COVERAGE

107 Citations

01020'10'12'14'16'18
Citations per Year
Semantic Scholar estimates that this publication has 107 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…