CpG Island Finding Using Graphical Models

  title={CpG Island Finding Using Graphical Models},
  author={Gang Ji and Tim Ng and Lingyun Huang},
CpG islands are short stretches in DNA sequence whose frequency of cytosine(C)and guanine (G) is higher than background of DNA sequence. They are around the promoter of frequently expressed genes. The conventional way to recognize CpG islands is to use the hidden Markov models (HMMs). While HMMs are known to suffer from not being able to capture long… CONTINUE READING