Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment.

@article{Shafren1995CoxsackievirusesBB,
  title={Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment.},
  author={D. Shafren and R. Bates and M. Agrez and R. Herd and G. Burns and R. Barry},
  journal={Journal of virology},
  year={1995},
  volume={69 6},
  pages={
          3873-7
        }
}
  • D. Shafren, R. Bates, +3 authors R. Barry
  • Published 1995
  • Medicine, Biology
  • Journal of virology
  • Receptor binding and subsequent cell-mediated internalization or disassembly are the initial steps in virus replication. Cell surface molecules that participate in this process are the primary determinants of virus tissue tropism. Monoclonal antibody blockade, immunoprecipitation, and DNA transfection were used to identify decay accelerating factor as a major cell attachment receptor for coxsackieviruses B1, B3, and B5. However, expression of human decay acceleration factor on the surface of… CONTINUE READING

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