Coxsackievirus B3-induced apoptosis and Caspase-3

  title={Coxsackievirus B3-induced apoptosis and Caspase-3},
  author={Jian Ping Yuan and Wei Zhao and Hong Tao Wang and Kai Wu and Tao Li and X K Guo and Shan Tong},
  journal={Cell Research},
ABSTRACTCell death can be classified into two categories: apoptosis and necrosis. Apoptotic pathway can be either caspase-dependent or caspase-independent. Caspase-independent cytopathic effect (CPE) has been described. In order to evaluate the pattern of HeLa cell death induced by Coxsackievirus B3 (CVB3) and whether apoptosis involves caspase activation, we co-cultivated HeLa cells with CVB3 and detected the cytopathic changes, the alteration of mRNA and protein expression of caspase-3 gene… CONTINUE READING


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