Coxsackievirus A21 binds to decay-accelerating factor but requires intercellular adhesion molecule 1 for cell entry.

@article{Shafren1997CoxsackievirusAB,
  title={Coxsackievirus A21 binds to decay-accelerating factor but requires intercellular adhesion molecule 1 for cell entry.},
  author={Darren R. Shafren and Douglas J. Dorahy and Rene Ingham and Gordon F. Burns and Richard D. Barry},
  journal={Journal of virology},
  year={1997},
  volume={71 6},
  pages={
          4736-43
        }
}
It is becoming increasingly apparent that many viruses employ multiple receptor molecules in their cell entry mechanisms. The human enterovirus coxsackievirus A21 (CAV21) has been reported to bind to the N-terminal domain of intercellular adhesion molecule 1 (ICAM-1) and undergo limited replication in ICAM-1-expressing murine L cells. In this study, we show that in addition to binding to ICAM-1, CAV21 binds to the first short consensus repeat (SCR) of decay-accelerating factor (DAF). Dual… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 121 CITATIONS, ESTIMATED 84% COVERAGE

Virus - host cell interactions in echovirus 1 infection

VIEW 14 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Systemic therapy of malignant human melanoma tumors by a common cold-producing enterovirus, coxsackievirus a21.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2004
VIEW 10 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1997
2019

CITATION STATISTICS

  • 19 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 42 REFERENCES

Decay-accelerating factor (CD55), a glycosylphosphatidylinositol-anchored complement regulatory protein, is a receptor for several echoviruses.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1994
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Structure and function of decay accelerating factor CD55.

  • The Journal of laboratory and clinical medicine
  • 1994
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL