Coxiella burnetii antigen-stimulated dendritic cells mediated protection against Coxiella burnetii in BALB/c mice.

@article{Wei2011CoxiellaBA,
  title={Coxiella burnetii antigen-stimulated dendritic cells mediated protection against Coxiella burnetii in BALB/c mice.},
  author={Yan Wei and Xile Wang and Xiaolu Xiong and Bohai Wen},
  journal={The Journal of infectious diseases},
  year={2011},
  volume={203 2},
  pages={
          283-91
        }
}
Coxiella burnetii is the etiological agent of human Q fever. In this study, adaptive transfer of mouse bone marrow-derived dendritic cells (BMDCs) stimulated with C. burnetii antigen, phase I whole-cell antigen (PIAg), lipopolysaccharide (LPS)-removed PIAg (PIIAg), protein antigen Com1, or SecB significantly reduced coxiella burden in recipient mice compared with control mice. Mice that received PIIAg-pulsed BMDCs displayed substantially lower coxiella burden than recipient mice of PIAg-pulsed… 
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Major Histocompatibility Complex Class II-Restricted, CD4+ T Cell-Dependent and -Independent Mechanisms Are Required for Vaccine-Induced Protective Immunity against Coxiella burnetii
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Mouse bone marrow‐derived dendritic cells can phagocytize the Sporothrix schenckii, and mature and activate the immune response by secreting interleukin‐12 and presenting antigens to T lymphocytes
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Results implied that dermal dendritic cells may participate in the induction of immune responses against S. schenckii infection in sporotrichosis.
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