Cowden syndrome: mucocutaneous lesions as precursors of internal malignancy

  title={Cowden syndrome: mucocutaneous lesions as precursors of internal malignancy},
  author={Panagiotis Stathopoulos and Anna Raymond and Michael Esson},
  journal={Oral and Maxillofacial Surgery},
Cowden syndrome is an autosomal-dominant hereditary cancer syndrome with high variability and susceptibility. It is characterized by multiple hamartomas and neoplasms of ectodermal, endodermal and mesodermal origin affecting many organs and also by the increased risk of development of internal malignancies. A 62-year-old woman was referred to our Maxillofacial Unit with a hamartomatous mass of the left lateral tongue which had slowly grown and was obstructing normal speech and restricting oral… CONTINUE READING
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