Cowden's syndrome affecting the mouth, gastrointestinal, and central nervous system: a case report and review of the literature.

@article{Leao2005CowdensSA,
  title={Cowden's syndrome affecting the mouth, gastrointestinal, and central nervous system: a case report and review of the literature.},
  author={J C Leao and Virg{\'i}nia Batista and Patr{\'i}cia de Barros Guimar{\~a}es and Josemir Belo and Stephen Porter},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2005},
  volume={99 5},
  pages={569-72}
}
Cowden's syndrome (CS) is a rare genodermatosis, of autosomal dominant inheritance and variable phenotype, principally characterized by the formation of hamartomas in various organs, including skin, thyroid, breast, brain, and gastrointestinal tract and by the increased risk for the development of malignancy. The present report details the features of a very rare presentation of Cowden's syndrome affecting not only the mouth and gastrointestinal mucosa but also the central nervous system. 
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