Cow's milk protein allergy and intolerance in infancy Some clinical, epidemiological and immunological aspects

@article{Hst1994CowsMP,
  title={Cow's milk protein allergy and intolerance in infancy Some clinical, epidemiological and immunological aspects},
  author={Arne H{\o}st},
  journal={Pediatric Allergy and Immunology},
  year={1994},
  volume={5}
}
  • A. Høst
  • Published 1994
  • Medicine
  • Pediatric Allergy and Immunology
Reproducible clinically abnormal reactions to cow's milk protein (CMP) may be due to the interaction between one or more milk proteins and one or more immune mechanisms, possibly any of the four basic types of hypersensitivity reactions. At present, evidence for type I, III and IV reactions against CMP has been demonstrated. Immunologically mediated reactions, mainly immediate IgE‐mediated reactions are defined as cow's milk protein allergy (CMPA). Non immunologically reactions against CMP are… Expand
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Data has been accumulating on the utility of diagnostic tools for mostly IgE-mediated milk allergy and allergenicity of milk from other mammalian species, although further studies are sought. Expand
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Cow's milk protein allergy. A multi-centre study: clinical and epidemiological aspects.
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Carrying out an appropriate diagnostic protocol in infants attending for suspected CMPA allows allergy to be ruled out in a high percentage of cases. Expand
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References

SHOWING 1-10 OF 366 REFERENCES
Cow's milk protein intolerance. Transient food intolerance of infancy.
TLDR
It now appears that typically the proximal small intestinal mucosa in this disorder is abnormal when biopsied, as described in this issue of the Archives by workers in Helsinki and in Paris. Expand
Allergy to cow's milk in the first year of life and its prevention.
TLDR
Parents of infants born to families with bilateral atopic histories may be able to prevent milk allergy by using dietary manipulations which include decreased prenatal maternal milk intake and while breast feeding as well as careful avoidance of milk products in the infant's diet during the first year of life. Expand
Allergy to cow's milk in the first year of life and its prevention.
TLDR
Parents of infants born to families with bilateral atopic histories may be able to prevent milk allergy by using dietary manipulations which include decreased prenatal maternal milk intake and while breast feeding as well as careful avoidance of milk products in the infant's diet during the first year of life. Expand
Immunoglobulin E and Immunoglobulin G4 Antibodies to Cow's Milk in Children with Cow's Milk Allergy
TLDR
An association between elevated total serum IgE and food allergy and an association between positive RAST to cow's milk and positive provocations in young children are confirmed. Expand
Cow's milk allergy in the first year of life. An Italian Collaborative Study.
The diagnosis of Cow's Milk Protein Allergy was considered in 303 infants aged less than 1 year, who presented with one or more of the following symptoms: acute reaction related to cow's milkExpand
Diagnostic value of skin and laboratory tests in cow's milk allergy/intolerance
TLDR
RAST, prick test and BHRT were more often positive in children exhibiting immediate reactions, and patch test and LPT more oftenpositive in those having delayed reactions to CM, while the sensitivity and specificity of the panel were 95% and 58%, respectively. Expand
THE SPECTRUM OF COW'S MILK ALLERGY IN CHILDHOOD Clinical, Gastroenterological and Immunological Studies
TLDR
A broad spectrum of reactions was observed including skin eruptions, respiratory symptoms and gastrointestinal disturbance and not all patients with gastrointestinal symptoms showed small bowel mucosal damage. Expand
Clinical manifestations of cows’ milk allergy in childhood. I. Associations with in‐vitro cellular immune responses
TLDR
A clinical diary score card was found to be a useful instrument to assess the response of non‐immediate reactions to milk ingestion and leucocyte inhibition factor (LIF) produced in response to α‐lactalbumin, β‐ lactoglobulin and α‐casein was assessed in the immediate and late reacting CMA patients as well as in the milk‐tolerant group. Expand
Value of immunologic tests in cow milk allergy
TLDR
No single laboratory method was sufficient to discriminate between the children who reacted to CM and those who did not, and the best combination of tests was measurements of CM‐specific IgE and the index of lymphocyte stimulation with BLG. Expand
Infants and children with cow milk allergy/intolerance
TLDR
Cow milk allergy/intolerance in infants and children may not be related to systemic activation of the complement system and may be elicited without considerable amounts of immunoreactive BLG in the circulation. Expand
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