Covid-19: Booster doses to be offered to 30 million people in UK

@article{Wise2021Covid19BD,
  title={Covid-19: Booster doses to be offered to 30 million people in UK},
  author={Jacqui Wise},
  journal={BMJ},
  year={2021},
  volume={374}
}
  • J. Wise
  • Published 14 September 2021
  • Psychology
  • BMJ

Public health impact of booster vaccination against COVID-19 in the UK during Delta variant dominance in autumn 2021.

TLDR
Booster vaccination during Delta variant predominance reduced the health burden of SARS-CoV-2 in the UK, releasing substantial NHS capacity and saving healthcare resources saved.

mRNA-based COVID-19 Vaccines Booster Dose: Benefits, Risks, and Coverage

TLDR
The aim of this mini- review was to answer some questions related to the benefits versus the risks of offering frequent boosters of mRNA vaccines for increasing the population immunity against COVID-19 infection considering the current policy of providing SARS-CoV-2 vaccine booster doses in rich countries versus those in relatively poor countries with limited access to vaccination.

Alpha, Beta, Delta, Omicron, and SARS-CoV-2 Breakthrough Cases: Defining Immunological Mechanisms for Vaccine Waning and Vaccine-Variant Mismatch

TLDR
Emerging data indicates decreasing circulating antibody levels as well as decreases in other immune correlates in vaccinated individuals, which must be interpreted with caution taking into consideration vaccine waning and the degree of vaccine variant-mismatch resulting in adaptive immune evasion by novel emerging SARS-CoV-2 variants.

The Population-Wide Risk-Benefit Profile of Extending the Primary COVID-19 Vaccine Course Compared with an mRNA Booster Dose Program

TLDR
It is demonstrated that the rate of vaccine efficacy waning has a significant impact on COVID-19 hospitalisations with the greatest effect in populations with lower vaccination coverage, and there was greater benefit associated with a booster vaccination strategy compared to targeting the unvaccinated population, once >50% of the population had received their primary vaccination course.

COVID-19 Booster Vaccines Administration in Different Countries

TLDR
The various COVID-19 booster vaccines that are being authorized and administered, the eligibility criteria for the different booster vaccines, and the extent of protection these booster vaccines provide in the United States (US), Israel, United Kingdom (UK), Singapore and Chile are discussed.

Covid-19: Booster dose reduces infections and severe illness in over 60s, Israeli study reports

Using the Israeli Ministry of Health database (for 30 July to 31August 2021), the researchers extracteddata on more than 1.1 million people aged 60 or over who hadbeen fully vaccinated at least

References

Covid-19: UK will offer third vaccine dose to severely immunosuppressed people

TLDR
People with specific conditions that make them particularly vulnerable to covid-19 may have received less protection against the virus from two vaccine doses, according to the JCVI.