Covariance PET patterns in early Alzheimer's disease and subjects with cognitive impairment but no dementia: utility in group discrimination and correlations with functional performance

@article{Scarmeas2004CovariancePP,
  title={Covariance PET patterns in early Alzheimer's disease and subjects with cognitive impairment but no dementia: utility in group discrimination and correlations with functional performance},
  author={N. Scarmeas and C. Habeck and E. Zarahn and K. Anderson and A. Park and H. J. Hilton and G. Pelton and M. Tabert and L. Honig and J. Moeller and D. Devanand and Y. Stern},
  journal={NeuroImage},
  year={2004},
  volume={23},
  pages={35-45}
}
Although multivariate analytic techniques might identify diagnostic patterns that are not captured by univariate methods, they have rarely been used to study the neural correlates of Alzheimer's disease (AD) or cognitive impairment. Nonquantitative H2(15)O PET scans were acquired during rest in 17 probable AD subjects selected for mild severity [mean-modified Mini Mental Status Examination (mMMS) 46/57; SD 5.1], 16 control subjects (mMMS 54; SD 2.5) and 23 subjects with minimal to mild… Expand
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