Covalently crosslinked chitosan hydrogel: properties of in vitro degradation and chondrocyte encapsulation.

@article{Hong2007CovalentlyCC,
  title={Covalently crosslinked chitosan hydrogel: properties of in vitro degradation and chondrocyte encapsulation.},
  author={Yi Min Hong and Haiqing Song and Yihong Gong and Zhengwei Mao and Changyou Gao and Jiacong C Shen},
  journal={Acta biomaterialia},
  year={2007},
  volume={3 1},
  pages={23-31}
}
In vitro degradation and chondrocyte-encapsulation of chitosan hydrogel made of crosslinkable and water-soluble chitosan derivative (CML) at neutral pH and body temperature were studied with respect to weight loss, cytoviability, DNA content and cell morphology. In vitro degradation of the chitosan hydrogels was sensitive to their crosslinking degree and existence of lysozyme in the solution. Chitosan hydrogel (Gel-I5) fabricated from 1% CML and 5mM ammonium persulfate (APS)/N,N,N',N… CONTINUE READING