Covalently bonded polysaccharide derivatives as chiral stationary phases in high-performance liquid chromatography.

  title={Covalently bonded polysaccharide derivatives as chiral stationary phases in high-performance liquid chromatography.},
  author={P. Franco and A. Senso and L. Oliveros and C. Minguillón},
  journal={Journal of chromatography. A},
  volume={906 1-2},
Polysaccharide derivatives have been extensively used as chromatographic chiral selectors in chiral stationary phases (CSPs) for the separation of enantiomers by HPLC. When coated onto a silica matrix, they represent nowadays one of the most popular type of CSPs. However, they are only compatible with a limited choice of solvents. The main drawback of these CSPs is related to the solubility of the chiral selector in a number of solvents, which limits their applicability. The different attempts… Expand
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