Covalent modifications of histones during development and disease pathogenesis

Abstract

Covalent modifications of histones are central to the regulation of chromatin dynamics, and, therefore, many biological processes involving chromatin, such as replication, repair, transcription and genome stability, are regulated by chromatin and its modifications. In this review, we discuss the biochemical, molecular and genetic properties of the enzymatic… (More)
DOI: 10.1038/nsmb1337

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Cite this paper

@article{Bhaumik2007CovalentMO, title={Covalent modifications of histones during development and disease pathogenesis}, author={Sukesh R Bhaumik and Edwin Smith and Ali Shilatifard}, journal={Nature Structural &Molecular Biology}, year={2007}, volume={14}, pages={1008-1016} }