Covalent linkage of heparin provides a stable anti‐coagulation surface of decellularized porcine arteries

@inproceedings{Liao2009CovalentLO,
  title={Covalent linkage of heparin provides a stable anti‐coagulation surface of decellularized porcine arteries},
  author={Dan Liao and Xinwen Wang and Peter H Lin and Qizhi Cathy Yao and Changyi Johnny Chen},
  booktitle={Journal of cellular and molecular medicine},
  year={2009}
}
Establishing thrombosis-resistant surface is crucial to develop tissue-engineered small diameter vascular grafts for arterial reconstructive procedures. The objective of this study was to evaluate the stability and anti-coagulation properties of heparin covalently linked to decellularized porcine carotid arteries. Cellular components of porcine carotid arteries were completely removed with chemical and physical means. Heparin was covalently linked to the decellularized vessels by a chemical… CONTINUE READING
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