Covalent immobilization of active lysozyme on Si/glass surface using alkoxy Fischer carbene complex on SAM.

Abstract

A cross-metathesis reaction between an alkene terminated self-assembled monolayer (SAM) on glass/Si wafer and an alkene tethered Fischer carbene complex yielded a functionalized surface. Rapid aminolysis of the Fischer carbene moieties permit efficient anchoring of amine containing molecules on such a surface. Attachment of 1-pyrenemethylamine was thus… (More)
DOI: 10.1039/c0ob00798f