Covalent bonding of PMMA, PBMA, and poly(HEMA)to hydroxyapatite particles.

  title={Covalent bonding of PMMA, PBMA, and poly(HEMA)to hydroxyapatite particles.},
  author={Qingxiu X Liu and Joost R. de Wijn and Clemens A van Blitterswijk},
  journal={Journal of biomedical materials research},
  volume={40 2},
In our earlier study, we showed that the surface hydroxyl groups of hydroxyapatite have the ability to react with organic isocyanate groups. In this study, the feasibility of grafting poly(methyl methacrylate) (PMMA), poly(n-butyl methacrylate) (PBMA), and Poly(hydroxyethyl methacrylate) [poly(HEMA)] by using the reaction of isocyanate groups with the hydroxyl groups on the surface of HA was investigated. Double bonds were introduced to the surface of HA via the coupling reaction of… CONTINUE READING


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