Course and Predictors of Cognitive Function in Patients With Prostate Cancer Receiving Androgen-Deprivation Therapy: A Controlled Comparison.

@article{Gonzalez2015CourseAP,
  title={Course and Predictors of Cognitive Function in Patients With Prostate Cancer Receiving Androgen-Deprivation Therapy: A Controlled Comparison.},
  author={Brian D Gonzalez and Heather S L Jim and Margaret Booth-Jones and Brent J. Small and Steven K. Sutton and Hui-Yi Lin and Jong Y. Park and Philippe Edouard Spiess and Mayer N. Fishman and Paul B. Jacobsen},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2015},
  volume={33 18},
  pages={2021-7}
}
PURPOSE Men receiving androgen-deprivation therapy (ADT) for prostate cancer may be at risk for cognitive impairment; however, evidence is mixed in the existing literature. Our study examined the impact of ADT on impaired cognitive performance and explored potential demographic and genetic predictors of impaired performance. PATIENTS AND METHODS Patients with prostate cancer were assessed before or within 21 days of starting ADT (n = 58) and 6 and 12 months later. Age- and education-matched… CONTINUE READING
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