Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit.

@article{Sims2014CouplingTA,
  title={Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit.},
  author={Natalie A Sims and Thomas J Martin},
  journal={BoneKEy reports},
  year={2014},
  volume={3},
  pages={481}
}
Coupling between bone formation and bone resorption refers to the process within basic multicellular units in which resorption by osteoclasts is met by the generation of osteoblasts from precursors, and their bone-forming activity, which needs to be sufficient to replace the bone lost. There are many sources of activities that contribute to coupling at remodeling sites, including growth factors released from the matrix, soluble and membrane products of osteoclasts and their precursors, signals… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 133 extracted citations

Similar Papers

Loading similar papers…