Coupling reaction of alkyl chlorides with silyl enolates catalyzed by indium trihalide.

Abstract

Indium(III) halide catalyzed not only the coupling of alkyl chlorides with silyl enolates derived from esters, ketones, and aldehydes to give a variety of alpha-alkylated carbonyl compounds but also one-pot, three-component reactions of aldehyde enolate, alkyl chloride, and allylsilane or alkynylsilane.

Cite this paper

@article{Nishimoto2007CouplingRO, title={Coupling reaction of alkyl chlorides with silyl enolates catalyzed by indium trihalide.}, author={Yoshihiro Nishimoto and Makoto Yasuda and Akio Baba}, journal={Organic letters}, year={2007}, volume={9 24}, pages={4931-4} }