Coupling of solid-phase microextraction continuous bed (monolithic) capillaries with capillary zone electrophoresis for direct analysis of drugs in biological fluids.

@article{Jarmalaviciene2008CouplingOS,
  title={Coupling of solid-phase microextraction continuous bed (monolithic) capillaries with capillary zone electrophoresis for direct analysis of drugs in biological fluids.},
  author={Reda Jarmalaviciene and Michał Szumski and Olga Korny{\vs}ova and Ewa Kłodzińska and Douglas Westerlund and Stanislas Krawczyk and Donatas Mickevicius and Bogusław Buszewski and Audrius Maru{\vs}ka},
  journal={Electrophoresis},
  year={2008},
  volume={29 8},
  pages={1753-60}
}
Hyperlink robust biocompatible solid-phase microextraction (SPME) devices were prepared using continuous bed (monolithic) restricted-access media (RAM) as the SPME capillary insert. The RAM-based SPME approach was able to simultaneously separate proteins from a biological sample, while directly extracting the active components of caffeine, paracetamol and acetylsalicylic acid from the drug NeoCitramonum. The devices were interfaced with a CZE system and fully automated analysis for sample… CONTINUE READING

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