Coupling between ATPase and force-generating attachment-detachment cycles of actomyosin in vitro.

Abstract

We have developed a high resolution force measurement system in vitro by manipulating a single actin filament attached to a microneedle. The system could resolve forces less than a piconewton, and has time resolution in the submillisecond range. We have used this system to detect force fluctuations produced by individual molecular interactions. We observed… (More)

Topics

Cite this paper

@article{Yanagida1993CouplingBA, title={Coupling between ATPase and force-generating attachment-detachment cycles of actomyosin in vitro.}, author={Toshio Yanagida and Akihiko Ishijima and Kazuhide Saito and Yosuke Harada}, journal={Advances in experimental medicine and biology}, year={1993}, volume={332}, pages={339-47; discussion 347-9} }