Coupling Oriented Hidden Markov Random Field Model with Local Clustering for Segmenting Blood Vessels and Measuring Spatial Structures in Images of Tumor Microenvironment


Interactions between cancer cells and factors within the tumor microenvironment (mE) are essential for understanding tumor development. The spatial relationships between blood vessel cells and cancer cells, e.g. tumor initiating cells (TICs), are an important parameter. Accurate segmentation of blood vessel is necessary for the quantization of their spatial… (More)
DOI: 10.1109/BIBM.2011.104


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